There were 783 viral detection episodes 440 (56%) associated with symptoms. Compared with single person households, individuals living with children experienced 3 additional weeks of virus detection. Children younger than 5 years reported symptoms more often and were more likely to have a virus detected than older participants (odds ratio 2.47, 95% confidence interval, 2.08–2.94 and OR 3.96, 95% CI, 3.35–4.70, respectively). Results. Participants reported symptoms in 23% and a virus was detected in 26% of person-weeks. Viral illnesses were defined as ≥1 consecutive weeks with the same virus detected with symptoms reported in ≥1 week. The FilmArray polymerase chain reaction (PCR) platform (BioFire Diagnostics, LLC) was used to detect 16 respiratory viruses. Methods. Twenty-six households (108 individuals) provided concurrent symptom and nasal swab data for 4166 person-weeks. Background. This study: (1) describes the viral etiology of respiratory illness by prospectively collecting weekly symptom diaries and nasal swabs from families for 1 year, (2) analyzed data by reported symptoms, virus, age, and family composition, and (3) evaluated the duration of virus detection.
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